Sort or type

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Possible Answers: ILK.

Random information on the term “ILK”:

4JOB, 4JOC, 4JOD

51205

66659

ENSG00000162836

ENSMUSG00000028093

Q9NPH0

Q8BP40

NM_016361
NM_001323625

NM_019800

NP_001310554
NP_057445

NP_062774.2
NP_062774

Lysophosphatidic acid phosphatase type 6 is an acid phosphatase enzyme that is encoded in humans by the ACP6 gene.

It acts as a phosphomonoesterase at low pHs. It is responsible for the hydrolysis of Lysophosphatidic acids (LPAs) to their respective monoacylglycerols and the release a free phosphate group in the process. The enzyme has higher activity for myristate-LPA (14 carbon chain), oleate-LPA (18 carbon chain and one unsaturated carbon-carbon bond), laurate-LPA (12 carbon chain) or palmitate-LPA (16 carbon chain). When the substrate is stearate-LPA (18 carbon chain), the enzyme has reduced activity. Phosphatidic acids can also be hydrolyzed by lysophosphatidic acid phosphatase, but at a significantly lower rate. The addition of the second fatty chain makes fitting into the active site much harder.

ILK on Wikipedia

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