This time we are looking on the crossword clue for: Piques.
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Possible Answers: IRES, IRKS, PETS, SNITS, AROUSES, VEXES.
Random information on the term “IRES”:
An internal ribosome entry site, abbreviated IRES, is a RNA element that allows for translation initiation in an cap-independent manner, as part of the greater process of protein synthesis. In eukaryotic translation, initiation typically occurs at the 5′ end of mRNA molecules, since 5′ cap recognition is required for the assembly of the initiation complex. The location for IRES elements is often in the 5’UTR, but can also occur elsewhere in mRNAs.
IRES sequences were first discovered in 1988 in the poliovirus (PV) and encephalomyocarditis virus (EMCV) RNA genomes in the labs of Nahum Sonenberg and Eckard Wimmer, respectively. They are described as distinct regions of RNA molecules that are able to recruit the eukaryotic ribosome to the mRNA. This process is also known as cap-independent translation. It has been shown that IRES elements have a distinct secondary or even tertiary structure, but similar structural features at the levels of either primary or secondary structure that are common to all IRES segments have not been reported to date.
Random information on the term “PETS”:
The Pet Travel Scheme (“PETS”) is a system which allows animals to travel easily between member countries without undergoing quarantine. A Pet Passport is a document that officially records information related to a specific animal, as part of that procedure. The effect is to drastically speed up and simplify travel with and transport of animals between member countries, compared to previous procedures, if the regulations are followed.
PETS was originally introduced for the benefit of animals entering or returning to the United Kingdom from other European Union countries, since historically the UK had very strong controls to safeguard against rabies including a compulsory six-month quarantine period on imports of many animals. On 1 October 2001 several European Union countries introduced the PETS scheme, under which animals from any member country may freely travel (with the correct procedure) to any other member country on approved carriers. Over time the scheme has rolled out to other countries such as the United States, Canada, Australia and New Zealand.