Cool

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Possible Answers: NEAT, NEATO, POISE, ICE, ABATE, FAN, RAD, SERENE, ICY, HIP, ALOOF, HEP, DEF, APLOMB, WITHIT, NONCHALANT, HIPNESS, LOSEINTENSITY.

Last seen on: –LA Times Crossword 5 Mar 21, Friday
The Washington Post Crossword – Oct 4 2020
LA Times Crossword 4 Oct 20, Sunday
LA Times Crossword 6 Oct 19, Sunday
NY Times Crossword 12 May 19, Sunday

Random information on the term “NEAT”:

Near-Earth Asteroid Tracking (NEAT) was a program run by NASA and the Jet Propulsion Laboratory, surveying the sky for near-Earth objects. NEAT was conducted from December 1995 until April 2007, at GEODSS on Hawaii (Haleakala-NEAT; 566), as well as at Palomar Observatory in California (Palomar-NEAT; 644). With the discovery of more than 40 thousand minor planets, NEAT has been one of the most successful programs in this field, comparable to the Catalina Sky Survey, LONEOS and Mount Lemmon Survey.

NEAT was the successor of the Palomar Planet-Crossing Asteroid Survey (PCAS).

The original principal investigator was Eleanor F. Helin, with co-investigators Steven H. Pravdo and David L. Rabinowitz.

NEAT has a cooperative agreement with the U.S. Air Force to use a GEODSS telescope located on Haleakala, Maui, Hawaii. GEODSS stands for Ground-based Electro-Optical Deep Space Surveillance and these wide field Air Force telescopes were designed to optically observe Earth orbital spacecraft. The NEAT team designed a CCD camera and computer system for the GEODSS telescope. The CCD camera format is 4096 × 4096 pixels and the field of view is 1.2° × 1.6°.

NEAT on Wikipedia

Random information on the term “ICE”:

1BMQ, 1IBC, 1ICE, 1RWK, 1RWM, 1RWN, 1RWO, 1RWP, 1RWV, 1RWW, 1RWX, 1SC1, 1SC3, 1SC4, 2FQQ, 2H48, 2H4W, 2H4Y, 2H51, 2H54, 2HBQ, 2HBR, 2HBY, 2HBZ, 3D6F, 3D6H, 3D6M, 3E4C, 3NS7, 5FNA

834

12362

ENSG00000137752

ENSMUSG00000025888

P29466

P29452

NM_033294
NM_033295

NM_009807

NP_150636
NP_150637

NP_033937.2
NP_033937

Caspase-1/Interleukin-1 converting enzyme (ICE) is an evolutionarily conserved enzyme that proteolytically cleaves other proteins, such as the precursors of the inflammatory cytokines interleukin 1β and interleukin 18 as well as the pyroptosis inducer Gasdermin D, into active mature peptides. It plays a central role in cell immunity as an inflammatory response initiator. Once activated through formation of an inflammasome complex, it initiates a proinflammatory response through the cleavage and thus activation of the two inflammatory cytokines, interleukin 1β (IL-1β) and interleukin 18 (IL-18) as well as pyroptosis, a programmed lytic cell death pathway, through cleavage of Gasdermin D. The two inflammatory cytokines activated by Caspase-1 are excreted from the cell to further induce the inflammatory response in neighboring cells.

ICE on Wikipedia

Random information on the term “ABATE”:

This category has only the following subcategory.

The following 25 pages are in this category, out of 25 total. This list may not reflect recent changes (learn more).

ABATE on Wikipedia

Random information on the term “FAN”:

Abyssal fans, also known as deep-sea fans, underwater deltas, and submarine fans, are underwater geological structures associated with large-scale sediment deposition and formed by turbidity currents. They can be thought of as an underwater version of alluvial fans and can vary dramatically in size, with widths from several kilometres to several thousands of kilometres (see Bengal Fan).

Abyssal (or submarine) fans are formed from turbidity currents.

Turbidity currents start when something, for example an earthquake (or just the inherent instability of newly deposited sediments), triggers sediments to be pushed over the edge of the continental shelf and down the continental slope, creating a submarine landslide. A dense slurry of muds and sands accelerates towards the foot of the slope until the gradient levels off and the turbidity current slows. The slowing current has a reduced ability to transport sediments and deposition of the coarser grains begins, creating a submarine fan. The current continues to slow down as it moves towards the continental rise until it reaches the level bottom of the ocean. This final result is a series of graded sediments of sand, silt and mud and these are known as turbidites, as described by the Bouma sequence.

FAN on Wikipedia

Random information on the term “RAD”:

Rad is a comic book supervillain in the Femforce comic published by A.C. Comics.

Rad possesses superhuman strength, together with the ability to fly (although only over short distances). Her true identity was Jennifer Burke, daughter of the original Miss Victory, who in the 1940s developed the “V-formula” to increase the strength/stamina of allied troops. The initial formula, V-45, turned Dan Barton, crack covert agent and boyfriend of Laura Wright, into the supervillain Black Commando. Joan Wayne was able to alter the formula, creating V-47, which only worked on herself and only for a short period of time, and she became the superheroine “Miss Victory”.

In the 1980s, the Black Commando force-fed some of the V-45 to Joan. In addition to permanent superstrength and youth, she developed the same paranoia and narcissism that the Black Commando had. She took the name “Rad” and became a ruthless mercenary. Eventually, Femforce was able to expunge the V-45 from her system and restore Joan’s normal personality.

RAD on Wikipedia

Random information on the term “ICY”:

Icelandic entrants in the Eurovision song contest.

The following 27 pages are in this category, out of 27 total. This list may not reflect recent changes (learn more).

ICY on Wikipedia

Random information on the term “HIP”:

The hip bone (os coxa, innominate bone, pelvic bone or coxal bone) is a large flat bone, constricted in the center and expanded above and below. In some vertebrates (including humans before puberty) it is composed of three parts: the ilium, ischium, and the pubis.

The two hip bones join at the pubic symphysis and together with the sacrum and coccyx (the pelvic part of the spine) comprise the skeletal component of the pelvis – the pelvic girdle which surrounds the pelvic cavity. They are connected to the sacrum, which is part of the axial skeleton, at the sacroiliac joint. Each hip bone is connected to the corresponding femur (thigh bone) (forming the primary connection between the bones of the lower limb and the axial skeleton) through the large ball and socket joint of the hip.

The hip bone is formed by three parts: ilium, ischium, and pubis. At birth, these three components are separated by hyaline cartilage. They join each other in a Y-shaped portion of cartilage in the acetabulum. By the end of puberty the three regions will have fused together, and by the age of 25 they will have ossified. The two hip bones join each other at the pubic symphysis. Together with the sacrum and coccyx, the hip bones form the pelvis.

HIP on Wikipedia

Random information on the term “HEP”:

Hepatitis is inflammation of the liver tissue. Some people have no symptoms whereas others develop yellow discoloration of the skin and whites of the eyes, poor appetite, vomiting, tiredness, abdominal pain, or diarrhea. Hepatitis may be temporary (acute) or long term (chronic) depending on whether it lasts for less than or more than six months. Acute hepatitis can sometimes resolve on its own, progress to chronic hepatitis, or rarely result in acute liver failure. Over time the chronic form may progress to scarring of the liver, liver failure, or liver cancer.

The most common cause worldwide is viruses. Other causes include heavy alcohol use, certain medications, toxins, other infections, autoimmune diseases, and non-alcoholic steatohepatitis (NASH). There are five main types of viral hepatitis: type A, B, C, D, and E. Hepatitis A and E are mainly spread by contaminated food and water. Hepatitis B is mainly sexually transmitted, but may also be passed from mother to baby during pregnancy or childbirth. Both hepatitis B and hepatitis C are commonly spread through infected blood such as may occur during needle sharing by intravenous drug users. Hepatitis D can only infect people already infected with hepatitis B.

HEP on Wikipedia

Random information on the term “DEF”:

Deferoxamine (DFOA), sold under the brand name Desferal, is a medication that binds iron and aluminium. It is specifically used in iron overdose, hemochromatosis either due to multiple blood transfusions or an underlying genetic condition, and aluminium toxicity in people on dialysis. It is used by injection into a muscle, vein, or under the skin.

Common side effects include pain at the site of injection, diarrhea, vomiting, fever, hearing loss, and eye problems. Severe allergic reactions including anaphylaxis and low blood pressure may occur. It is unclear if use during pregnancy or breastfeeding is safe for the baby. Deferoxamine is a siderophore from the bacteria Streptomyces pilosus.

Deferoxamine was approved for medical use in the United States in 1968. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 6.76 to 13.52 USD per dose. In the United States a course of treatment costs more than 200 USD.

DEF on Wikipedia