This time we are looking on the crossword clue for: Air-leak sound.
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Possible Answers: SSS, SSSS.
Random information on the term “SSS”:
The SSS islands is an acronym which refers to three island territories in the Lesser Antilles that are under Dutch sovereignty:
Sint Maarten is a constituent country of the Kingdom of the Netherlands and is the southern half of the island of Saint Martin (the northern half is the French Collectivity of Saint Martin). The islands of Saba and Sint Eustatius are public bodies of the Netherlands.
The acronym is analogous to the ABC islands, consisting of Aruba, Bonaire and Curaçao, and the BES islands, consisting of Bonaire, Sint Eustatius and Saba, both of which are also part of the Kingdom of the Netherlands. All six island territories were formerly part of the Netherlands Antilles.
Saint Martin was split between the Netherlands and France in 1648. The Dutch part became a single Dutch colony in 1818 as Sint Eustatius and Dependencies when France returned its possessions after the Napoleonic Wars. This colony was merged in 1828 with the colonies Curaçao and Dependencies (the ABC islands) and Suriname with a capital in Paramaribo. When this merge was partly reversed in 1845, the Dutch part of the SSS islands became part of Curaçao and Dependencies with Willemstad as capital. This colony became the Netherlands Antilles in 1952. The Dutch part of the SSS islands initially formed the single “island area” (Dutch: eilandgebied, the main administrative division of the Netherlands Antilles, governed by an Island council) the Leeward islands (Dutch: de Bovenwindse eilanden) until 1983.
Random information on the term “SSSS”:
The Scandinavian Simvastatin Survival Study (also known under the abbreviation 4S) is a multicenter clinical trial that was performed in the 1990s in Scandinavia.
The objective of the study was to assess effect of a cholesterol-lowering drug called simvastatin on mortality and morbidity in a group of 4444 patients with coronary heart disease, ages between 35 and 70 years. The patients exhibited moderate hypercholesterolemia, between 5.5 and 8.0 mmol/l. The trial showed that treatment of patients suffering from coronary heart disease with simvastatin had a lowering effect on mortality and morbidity.
2223 patients were assigned placebo and 2221 were assigned simvastatin treatment for a median period of 5.4 years. There was a 30% relative reduction in the risk of death with simvastatin treatment. The absolute coronary-heart-disease mortality was reduced from 8.5% to 5.0%, making the number needed to treat around 30 (30 patients would need to be treated to prevent one death). Additionally there was no excess morbidity of non-cardiac deaths from causes like cancer or suicide, a concern that has occasionally arisen in respect to statins.